:root{--alan-primary: #d32f2f;--alan-primary-light: #ef5350;--alan-primary-dark: #b71c1c;--alan-primary-lighter: #ffebee;--alan-primary-medium: #e53935;--alan-secondary: #c62828;--alan-secondary-light: #e57373;--alan-secondary-dark: #b71c1c;--alan-accent: #0d9488;--alan-accent-light: #2dd4bf;--alan-accent-dark: #0f766e;--alan-success: #388e3c;--alan-success-light: #66bb6a;--alan-success-dark: #2e7d32;--alan-warning: #f57c00;--alan-warning-light: #ff9800;--alan-warning-dark: #e65100;--alan-gray-50: #f9fafb;--alan-gray-100: #f3f4f6;--alan-gray-200: #e5e7eb;--alan-gray-300: #d1d5db;--alan-gray-400: #9ca3af;--alan-gray-500: #6b7280;--alan-gray-600: #4b5563;--alan-gray-700: #374151;--alan-gray-800: #1f2937;--alan-gray-900: #111827;--alan-text-primary: #111827;--alan-text-secondary: #6b7280;--alan-text-tertiary: #6b7280;--alan-text-light: #9ca3af;--alan-text-white: #ffffff;--alan-bg-primary: #ffffff;--alan-bg-secondary: #ffffff;--alan-bg-tertiary: #f3f4f6;--alan-bg-gradient-start: #d32f2f;--alan-bg-gradient-end: #b71c1c;--alan-border-light: #e5e7eb;--alan-border-medium: #d1d5db;--alan-border-dark: #9ca3af;--alan-shadow-card: 0 2px 8px rgba(0, 0, 0, .06), 0 1px 3px rgba(0, 0, 0, .04);--alan-shadow-sm: 0 1px 2px 0 rgba(0, 0, 0, .05);--alan-shadow-md: 0 2px 4px rgba(0, 0, 0, .06), 0 1px 2px rgba(0, 0, 0, .04);--alan-shadow-lg: 0 4px 6px -1px rgba(0, 0, 0, .07), 0 2px 4px -1px rgba(0, 0, 0, .05);--alan-shadow-xl: 0 10px 15px -3px rgba(0, 0, 0, .08), 0 4px 6px -2px rgba(0, 0, 0, .05);--chart-color-1: #DC2626;--chart-color-2: #4338CA;--chart-color-3: #0D9488;--chart-color-4: #F59E0B;--chart-color-5: #4f46e5;--chart-color-6: #388e3c;--chart-color-7: #f28482;--chart-color-8: #6b7280}[data-theme=dark]{--alan-bg-primary: #1f2937;--alan-bg-secondary: #111827;--alan-text-primary: #f9fafb;--alan-text-secondary: #d1d5db}*{margin:0;padding:0;box-sizing:border-box}body{font-family:-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Oxygen,Ubuntu,Cantarell,Fira Sans,Droid Sans,Helvetica Neue,sans-serif;-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;background:var(--alan-bg-tertiary);min-height:100vh}.App{min-height:100vh;display:flex;flex-direction:column}.App-header{background:var(--alan-bg-primary);padding:.6rem 2rem;text-align:center;box-shadow:var(--alan-shadow-md);border-bottom:2px solid var(--alan-primary-lighter);position:sticky;top:0;z-index:100}.App-header h1{color:var(--alan-primary);margin-bottom:.5rem;font-size:2.5rem;font-weight:700}.App-header p{color:var(--alan-text-secondary);font-size:1.1rem}.tabs{display:flex;justify-content:center;gap:1rem;padding:1.5rem;background:var(--alan-bg-primary);box-shadow:var(--alan-shadow-sm);flex-wrap:wrap;border-bottom:1px solid var(--alan-border-light)}.tabs button{padding:.75rem 1.5rem;font-size:1rem;border:2px solid var(--alan-primary);background:var(--alan-bg-primary);color:var(--alan-primary);border-radius:8px;cursor:pointer;transition:all .3s ease;font-weight:500}.tabs button:hover{background:var(--alan-primary);color:var(--alan-text-white);transform:translateY(-2px);box-shadow:var(--alan-shadow-md)}.tabs button.active{background:var(--alan-primary);color:var(--alan-text-white);box-shadow:var(--alan-shadow-lg);border-color:var(--alan-primary-dark)}.App-main{flex:1;padding:.875rem 2.5rem;max-width:1600px;width:100%;margin:0 auto}.global-date-filter-sticky{position:sticky;top:5.5rem;z-index:90;margin-left:-2.5rem;margin-right:-2.5rem;margin-bottom:1rem}.phase-info-wrap{position:relative;display:inline-flex;align-items:center;gap:.25rem;font-size:.8rem}.phase-info-wrap .phase-info-tooltip{position:absolute;left:0;top:100%;margin-top:6px;padding:8px 10px;background:var(--alan-text-primary);color:var(--alan-bg-primary);font-size:.75rem;line-height:1.4;border-radius:8px;white-space:normal;max-width:280px;opacity:0;visibility:hidden;pointer-events:none;transition:opacity .2s ease,visibility .2s ease;z-index:1000;box-shadow:var(--alan-shadow-md);font-weight:400}.phase-info-wrap:hover .phase-info-tooltip,.phase-info-wrap:focus-within .phase-info-tooltip{opacity:1;visibility:visible}.chart-container{background:#fff;border-radius:16px;padding:1.5rem;margin-bottom:0;box-shadow:var(--alan-shadow-card);transition:transform .3s ease,box-shadow .3s ease;border:1px solid var(--alan-border-light);width:100%}.size-1-2{grid-column:span 3;display:flex;min-height:0}.size-1-3{grid-column:span 2;display:flex;min-height:0}.size-2-3{grid-column:span 4;display:flex;min-height:0}.size-1-4{grid-column:span 1;display:flex;min-height:0}.full-width{grid-column:1 / -1;display:flex;min-height:0}.chart-container:hover{box-shadow:var(--alan-shadow-xl);border-color:var(--alan-primary-lighter)}.overview-card{width:100%;min-height:0!important;box-shadow:0 1px 3px #0000000f}.overview-card-clickable{cursor:pointer}.overview-card-active:focus-visible{outline:2px solid var(--alan-primary);outline-offset:2px}.chart-container h2{color:var(--alan-text-primary);margin-top:0;margin-bottom:8px;padding-bottom:0;font-size:1rem;text-align:left;font-weight:600}.chart-container p,.chart-container label{text-align:left}.dashboard-grid{display:grid;grid-template-columns:repeat(6,1fr);gap:.75rem;width:100%;max-width:100%;margin:0 auto;align-items:stretch;transition:all .3s ease}.dashboard-grid-export{display:grid;grid-template-columns:repeat(2,1fr);gap:1rem;width:100%;max-width:100%;margin:0 auto;align-items:stretch;transition:all .3s ease}@media (min-width: 768px){.dashboard-grid-export{grid-template-columns:repeat(4,1fr)}}.dashboard-grid .chart-container.full-width{grid-column:1 / -1;max-width:100%;width:100%}.studies-by-country-section .studies-by-country-grid{flex:1;min-height:55vh}.studies-by-country-grid{display:grid;grid-template-columns:1fr 1fr;gap:1rem;align-items:stretch;min-height:0}@media (max-width: 900px){.studies-by-country-grid{grid-template-columns:1fr}.studies-by-country-section .studies-by-country-grid{min-height:50vh}.App-main{padding-left:1.25rem;padding-right:1.25rem}.global-date-filter-sticky{margin-left:-1.25rem;margin-right:-1.25rem}}.studies-by-country-map-wrap{min-height:400px;height:100%;display:flex;flex-direction:column;background-color:#f0f4f8;border-radius:8px;overflow:hidden}.studies-by-country-map-wrap>*{flex:1;min-height:0}.studies-by-country-list-wrap{min-height:400px;display:flex;flex-direction:column;overflow:hidden}.dashboard-grid-export .size-1-2,.dashboard-grid-export .size-1-3,.dashboard-grid-export .size-2-3,.dashboard-grid-export .size-1-4,.dashboard-grid-export .full-width{grid-column:span 1}@media (min-width: 768px){.dashboard-grid-export .size-1-2,.dashboard-grid-export .size-1-3,.dashboard-grid-export .size-2-3,.dashboard-grid-export .size-1-4,.dashboard-grid-export .full-width{grid-column:span 1}}.global-date-range-track-wrap{position:relative;height:18px;display:flex;align-items:center}.global-date-range-track-wrap:before{content:"";position:absolute;left:0;right:0;height:3px;border-radius:2px;background:var(--alan-border-light);pointer-events:none}.global-date-range-fill{position:absolute;top:calc(50% - 1.5px);height:3px;border-radius:2px;background:var(--alan-primary);opacity:.75;pointer-events:none}.global-date-range-input{position:absolute;left:0;right:0;width:100%;height:18px;margin:0;background:transparent;-webkit-appearance:none;-moz-appearance:none;appearance:none;pointer-events:none}.global-date-range-input::-webkit-slider-thumb{-webkit-appearance:none;-moz-appearance:none;appearance:none;width:13px;height:13px;margin-top:-5px;border-radius:50%;background:var(--alan-primary);border:2px solid white;box-shadow:0 1px 4px #0003;cursor:grab;pointer-events:auto;transition:transform .1s ease,box-shadow .1s ease}.global-date-range-input::-webkit-slider-thumb:hover{transform:scale(1.25);box-shadow:0 2px 8px #00000040}.global-date-range-input::-webkit-slider-thumb:active{cursor:grabbing;transform:scale(1.15)}.global-date-range-input::-moz-range-thumb{width:13px;height:13px;border-radius:50%;background:var(--alan-primary);border:2px solid white;box-shadow:0 1px 4px #0003;cursor:grab;pointer-events:auto}.global-date-range-input::-webkit-slider-runnable-track{height:3px;background:transparent}.global-date-range-input::-moz-range-track{height:3px;background:transparent}.global-date-range-high{z-index:1}.chart-container{min-height:260px;height:100%;max-width:100%;display:flex;flex-direction:column;transition:min-height .3s ease,height .3s ease}.chart-container.chart-container-export,.chart-container-export{min-height:200px!important;height:280px!important;max-width:100%;display:flex;flex-direction:column;transition:min-height .3s ease,height .3s ease;overflow:hidden;padding:.75rem!important}.chart-container-export .chart-container{min-height:200px!important;height:280px!important;overflow:hidden;padding:.75rem!important}.chart-container-export h2{font-size:.9rem!important;margin-bottom:.5rem!important;margin-top:0!important;line-height:1.2!important}.chart-container-export p{font-size:.7rem!important;margin-bottom:.5rem!important;line-height:1.2!important}.chart-container-export label{font-size:.7rem!important}.chart-container-export select,.chart-container-export input{font-size:.7rem!important;padding:.25rem .5rem!important}.chart-container-export>div:not([data-export-ignore]){margin-bottom:.5rem!important}.chart-container-export>div:not([data-export-ignore]):last-child{margin-bottom:0!important}.chart-container-export>div:not([data-export-ignore])>div[style*=height]{height:260px!important;min-height:260px!important;max-height:260px!important}.chart-container-export div:not([data-export-ignore])[style*="height: '400px'"],.chart-container-export div:not([data-export-ignore])[style*="height: 400px"],.chart-container-export div:not([data-export-ignore])[style*='height: "400px"'],.chart-container-export div:not([data-export-ignore])[style*="height: '500px'"],.chart-container-export div:not([data-export-ignore])[style*="height: 500px"],.chart-container-export div:not([data-export-ignore])[style*='height: "500px"']{height:260px!important;min-height:260px!important;max-height:260px!important}.chart-container-export>div:not([data-export-ignore]):last-child,.chart-container-export>div:not([data-export-ignore])>div:last-child{height:260px!important;min-height:260px!important;max-height:260px!important;flex:0 0 260px!important}.chart-container-export [style*=gap]:not([data-export-ignore]){gap:.5rem!important}.chart-container-export [style*=padding]:not([data-export-ignore]){padding:.5rem!important}.chart-container-export [style*=marginBottom]:not([data-export-ignore]){margin-bottom:.5rem!important}.chart-container-export button{padding:.25rem .5rem!important;font-size:.7rem!important}.chart-container-export svg{max-height:260px!important}.export-mode-height-fix{height:260px!important;min-height:260px!important;max-height:260px!important;overflow:hidden!important}.export-mode-content{height:280px!important;min-height:280px!important;max-height:280px!important;overflow:hidden!important}.export-mode-content>div{height:260px!important;min-height:260px!important;max-height:260px!important}.export-mode-content div[style*=height]{height:260px!important;min-height:260px!important;max-height:260px!important}.export-mode-content *{margin-top:.25rem!important;margin-bottom:.25rem!important}.export-mode-content h2{margin-top:0!important;margin-bottom:.25rem!important}.export-mode-content>*:first-child{margin-top:0!important}.export-mode-content>*:last-child{margin-bottom:0!important}@media (max-width: 1200px){.dashboard-grid{grid-template-columns:repeat(auto-fit,minmax(400px,1fr))}}@media (max-width: 768px){.dashboard-grid{grid-template-columns:1fr;gap:.75rem}.chart-container{min-height:260px;grid-column:span 1!important}}.App-footer{background:var(--alan-bg-primary);padding:.75rem 1.5rem;text-align:center;color:var(--alan-text-secondary);font-size:.8rem;box-shadow:var(--alan-shadow-md);border-top:1px solid var(--alan-border-light)}@media (max-width: 768px){.App-header h1{font-size:1.4rem}.tabs{padding:.75rem}.tabs button{padding:.4rem .75rem;font-size:.85rem}.App-main{padding:.75rem}.chart-container{padding:1.25rem}}.alan-range-slider{-webkit-appearance:none;-moz-appearance:none;appearance:none}.alan-range-slider::-webkit-slider-thumb{-webkit-appearance:none;-moz-appearance:none;appearance:none;width:18px;height:18px;border-radius:50%;background:var(--alan-primary);cursor:pointer;border:2px solid white;box-shadow:0 2px 4px #0003;transition:all .2s ease}.alan-range-slider::-webkit-slider-thumb:hover{background:var(--alan-primary-dark);transform:scale(1.1);box-shadow:0 3px 6px #0000004d}.alan-range-slider::-webkit-slider-runnable-track{height:6px;border-radius:3px}.alan-range-slider::-moz-range-thumb{width:18px;height:18px;border-radius:50%;background:var(--alan-primary);cursor:pointer;border:2px solid white;box-shadow:0 2px 4px #0003;transition:all .2s ease}.alan-range-slider::-moz-range-thumb:hover{background:var(--alan-primary-dark);transform:scale(1.1);box-shadow:0 3px 6px #0000004d}.alan-range-slider::-moz-range-track{height:6px;border-radius:3px}@keyframes slideUp{0%{opacity:0;transform:translate(-50%) translateY(20px)}to{opacity:1;transform:translate(-50%) translateY(0)}}@keyframes spin{0%{transform:rotate(0)}to{transform:rotate(360deg)}}